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PADI4

PIK3C3,即肽酰基精氨酸脫亞氨酶4,別名PAD4、PDI4、PDI5、PADI5。PIK3C3由人類PADI4基因編碼,該基因位于1號染色體的p36.13區(qū)域。PIK3C3是一種鈣依賴性酶,通過催化精氨酸殘基向瓜氨酸殘基的轉(zhuǎn)化過程,參與蛋白質(zhì)的瓜氨酸化這一翻譯后修飾。PIK3C3通過組蛋白瓜氨酸化調(diào)節(jié)基因轉(zhuǎn)錄活性,影響多種疾病的發(fā)生和發(fā)展,包括自身免疫性疾病、腫瘤、急性冠狀動脈綜合征等。PIK3C3的異常調(diào)節(jié)與類風(fēng)濕關(guān)節(jié)炎、腫瘤發(fā)展和多發(fā)性硬化癥等多種疾病相關(guān),被認(rèn)為是治療這些疾病的潛在靶點。

熱銷產(chǎn)品

Recombinant Human Protein-arginine deiminase type-4 (PADI4) (CSB-EP890757HU)

驗證數(shù)據(jù)

CSB-EP890757HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PADI4 Antibody (CSB-PA890757ESR2HU)

驗證數(shù)據(jù)

CSB-PA890757ESR2HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA890757ESR2HU at dilution of 1:100

CSB-PA890757ESR2HU

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA890757ESR2HU at dilution of 1:100

Human protein-arginine deiminase type-4(PADI4) ELISA kit (CSB-E16219h)

驗證數(shù)據(jù)

CSB-E16219h 標(biāo)準(zhǔn)曲線

貨號:CSB-E16219h

規(guī)格:96T/48T

靈敏度:0.039 ng/mL

檢測范圍:0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PADI4 Antibodies

PADI4 for Homo sapiens (Human)

PADI4 Proteins

PADI4 Proteins for Homo sapiens (Human)

PADI4 ELISA Kit

PADI4 ELISA Kit for Homo sapiens (Human)